GABA

$\gamma$-Aminobutyric acid. The primary inhibitory neurotransmitter in adult mammalian Central Nervous System.

If Glutamate is the brain’s accelerator, GABA is the brakes. Binds to GABA receptors (GABA${}_A$, GABA${}_B$, GABA${}_C$).

Function

Maintains homeostatic balance by preventing over-firing. Critical for orchestration of Neural Circuit rhythms.

Without sufficient GABAergic inhibition, neural networks become hyperexcitable—leading to seizures, anxiety, and loss of temporal precision in circuit dynamics.