Graph View
Nootropic Compounds
Showing 22 of 22 entries
PPAP
Typecatecholamine activity enhancer
Pathwaysdopamine, norepinephrine
BenefitsADHD/Focus, Depression, Longevity, Motivation, Wakefulness
Stacks-well-withLisdexamfetamine
Lisdexamfetamine
Typeamphetamine prodrug
Pathwaysdopamine, norepinephrine
Brain-regionsprefrontal cortex, striatum
BenefitsADHD/Focus, Motivation, Wakefulness
Stacks-well-withGuanfacine, Bromantane, N-Acetylsemax
Dihexa
Typenootropic peptide
TargetsHGF receptor, MET receptor
ProcessesLTP, neurogenesis
Brain-regionshippocampus
ACD-856
TypeTrkB PAM
ProcessesLTP, neurogenesis
Brain-regionshippocampus
BenefitsDepression, Drug Cravings, Higher Cognition, Memory, Neuroplasticity
Stacks-well-withTAK-653, glutamatergics, neurogenics
N-Acetylsemax
Typenootropic peptide
TargetsTrkB
PathwaysBDNF, dopamine, serotonin, norepinephrine
Processesneurogenesis
BenefitsADHD/Focus, Depression, Higher Cognition, Memory, Motivation, Neuroplasticity
Stacks-well-withN-Acetylselank, ACD-856, Lisdexamfetamine
Selegiline
TypeMAO-B inhibitor
TargetsMAO-B
Pathwaysdopamine, phenethylamine
Brain-regionsstriatum
BenefitsADHD/Focus, Depression, Longevity, Motivation, Neuroplasticity, Wakefulness
Neboglamine
TypeNMDA glycine PAM
TargetsNMDA receptor, NR2B
Brain-regionshippocampus
BenefitsHigher Cognition, Memory, Neuroplasticity
Guanfacine
Typeα2A adrenergic agonist
Targetsα2A adrenoceptor
Pathwaysnorepinephrine, cAMP
Brain-regionsprefrontal cortex, DLPFC
BenefitsADHD/Focus, Anxiety, Drug Cravings, Higher Cognition, Motivation, PFC Top-Down Control
Stacks-well-withLisdexamfetamine
Zinc Gluconate
Typemineral supplement
Targetsdopamine transporter, NMDA receptor
Pathwaysdopamine
BenefitsADHD/Focus, Depression, General Health, Illness Prevention, Motivation, Nutritional Supplementation
Stacks-well-withLisdexamfetamine
Bromantane
Typedopaminergic
BenefitsADHD/Focus, Anxiety, Depression, Memory, Motivation, Neuroplasticity, Wakefulness
Stacks-well-withLisdexamfetamine, psychostimulants
TAK-653
TypeAMPA PAM
TargetsAMPA Receptor, GluR2
ProcessesLTP
Brain-regionsprefrontal cortex, hippocampus
BenefitsADHD/Focus, Depression, Higher Cognition, Memory, Neuroplasticity
Stacks-well-withACD-856, Neboglamine
AF710B
TypeM1-Sigma1 agonist
PathwayscAMP, ERK, Acetylcholine
Brain-regionsDLPFC, hippocampus
BenefitsHigher Cognition, Memory, Neuroplasticity, Longevity
Stacks-well-withCerebrolysin, ACD-856
Methylene Blue
TypeRIMA
TargetsMAO, acetylcholinesterase
Pathwayscytochrome c oxidase, nitric oxide
Processesmitochondrial biogenesis
BenefitsADHD/Focus, Antioxidation, Bipolar, Cancer Prevention, Depression, General Health, Higher Cognition, Illness Prevention, Longevity, Memory
Stacks-well-withSertraline, serotonergic antidepressants (WITH CAUTION)
Tropisetron
Typeα7 nAChR agonist
Targetsα7 nAChR, 5-HT3 receptor, SIRT1
PathwaysAcetylcholine, cAMP, serotonin
ProcessesLTP, neurogenesis
Brain-regionsprefrontal cortex, hippocampus
BenefitsADHD/Focus, Higher Cognition, Memory, Motivation, PFC Top-Down Control
Stacks-well-withNicotine (enhances and prolongs effects)
Usmarapride
Type5-HT4 partial agonist
Targets5-HT4 receptor
ProcessesLTP, neurogenesis
Brain-regionshippocampus
BenefitsMemory, Higher Cognition, Depression, Anxiety, Neuroplasticity
Stacks-well-withACD-856, Tropisetron
Semax
Typenootropic peptide
TargetsTrkB
PathwaysBDNF, dopamine, serotonin, norepinephrine
Processesneurogenesis
BenefitsADHD/Focus, Anxiety, Wakefulness
BPAP
Typecatecholamine activity enhancer
Pathwaysdopamine, norepinephrine
BenefitsADHD/Focus, Depression, Longevity, Motivation
ABT-089
Typeα4β2 nAChR partial agonist
Targetsα4β2 nicotinic receptor
PathwaysAcetylcholine
Processesattentional filtering, working memory
Brain-regionsprefrontal cortex, thalamus
BenefitsAttention, Working memory, Cognitive filtering
Stacks-well-withTropisetron
BPN14770
TypePDE4D inhibitor
TargetsPDE4D
ProcessesLTP, synaptic consolidation
Brain-regionshippocampus, prefrontal cortex
BenefitsMemory consolidation, LTP, Neuroplasticity
Stacks-well-withACD-856
Fasoracetam
TypemGluR2/3 agonist / GABA-B upregulator
TargetsmGluR2, mGluR3, GABA-B receptor
Processesreceptor resensitization, E/I balance
Brain-regionsprefrontal cortex, hippocampus
BenefitsReceptor resensitization, E/I balance restoration, Anxiolytic
KW-6356
TypeA2A adenosine receptor antagonist
TargetsA2A adenosine receptor, D2 receptor
Processesdopaminergic signaling
Brain-regionsstriatum, basal ganglia
BenefitsMotivation, Drive, Goal-directed behavior
Stacks-well-withBromantane
Tabernanthalog
TypeTrkB partial agonist / 5-HT2A partial agonist
TargetsTrkB, 5-HT2A receptor
Processessynaptogenesis, dendritic growth
Brain-regionshippocampus, prefrontal cortex
BenefitsDendritic growth, Synaptogenesis, Neural repair, Neuroplasticity
Stacks-well-withCerebrolysin