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Nootropic Compounds

Showing 22 of 22 entries

PPAP

BasenamePPAP
Typecatecholamine activity enhancer
Pathwaysdopamine, norepinephrine
BenefitsADHD/Focus, Depression, Longevity, Motivation, Wakefulness
Stacks-well-withLisdexamfetamine

Lisdexamfetamine

BasenameLisdexamfetamine
Typeamphetamine prodrug
Targetsdopamine transporter, norepinephrine transporter
Pathwaysdopamine, norepinephrine
Brain-regionsprefrontal cortex, striatum
BenefitsADHD/Focus, Motivation, Wakefulness
Stacks-well-withGuanfacine, Bromantane, N-Acetylsemax

Dihexa

BasenameDihexa
Typenootropic peptide
TargetsHGF receptor, MET receptor
PathwaysBDNF, NGF
ProcessesLong Term Potentiation, neurogenesis
Brain-regionshippocampus

ACD-856

BasenameACD-856
TypeTrkB PAM
TargetsTrkB, TrkA, TrkC
PathwaysBDNF, NGF
ProcessesLong Term Potentiation, neurogenesis
Brain-regionshippocampus
BenefitsDepression, Drug Cravings, Higher Cognition, Memory, Neuroplasticity
Stacks-well-withTAK-653, glutamatergics, neurogenics

N-Acetylsemax

BasenameN-Acetylsemax
Typenootropic peptide
TargetsTrkB
PathwaysBDNF, dopamine, serotonin, norepinephrine
Processesneurogenesis
BenefitsADHD/Focus, Depression, Higher Cognition, Memory, Motivation, Neuroplasticity
Stacks-well-withN-Acetylselank, ACD-856, Lisdexamfetamine

Selegiline

BasenameSelegiline
TypeMAO-B inhibitor
TargetsMAO-B
Pathwaysdopamine, phenethylamine
Brain-regionsstriatum
BenefitsADHD/Focus, Depression, Longevity, Motivation, Neuroplasticity, Wakefulness

Neboglamine

BasenameNeboglamine
TypeNMDA glycine PAM
TargetsNMDA receptor, NR2B
PathwaysD-Serine, BDNF
ProcessesLong Term Potentiation, LTD
Brain-regionshippocampus
BenefitsHigher Cognition, Memory, Neuroplasticity
Stacks-well-withTAK-653, ACD-856

Guanfacine

BasenameGuanfacine
Typeα2A adrenergic agonist
Targetsα2A adrenoceptor
Pathwaysnorepinephrine, cAMP
Brain-regionsprefrontal cortex, DLPFC
BenefitsADHD/Focus, Anxiety, Drug Cravings, Higher Cognition, Motivation, PFC Top-Down Control
Stacks-well-withLisdexamfetamine

Zinc Gluconate

BasenameZinc Gluconate
Typemineral supplement
Targetsdopamine transporter, NMDA receptor
Pathwaysdopamine
BenefitsADHD/Focus, Depression, General Health, Illness Prevention, Motivation, Nutritional Supplementation
Stacks-well-withLisdexamfetamine

Bromantane

BasenameBromantane
Typedopaminergic
Targetsdopamine transporter, serotonin transporter
Pathwaysdopamine, serotonin, BDNF
BenefitsADHD/Focus, Anxiety, Depression, Memory, Motivation, Neuroplasticity, Wakefulness
Stacks-well-withLisdexamfetamine, psychostimulants

TAK-653

BasenameTAK-653
TypeAMPA PAM
TargetsAMPA Receptor, GluR2
PathwaysmTOR, BDNF, ERK
ProcessesLong Term Potentiation
Brain-regionsprefrontal cortex, hippocampus
BenefitsADHD/Focus, Depression, Higher Cognition, Memory, Neuroplasticity
Stacks-well-withACD-856, Neboglamine

AF710B

BasenameAF710B
TypeM1-Sigma1 agonist
TargetsM1 muscarinic receptor, Sigma-1 receptor
PathwayscAMP, ERK, Acetylcholine
ProcessesLong Term Potentiation, LTD
Brain-regionsDLPFC, hippocampus
BenefitsHigher Cognition, Memory, Neuroplasticity
Stacks-well-withCerebrolysin, ACD-856

Methylene Blue

BasenameMethylene Blue
TypeRIMA
TargetsMAO, acetylcholinesterase
Pathwayscytochrome c oxidase, nitric oxide
Processesmitochondrial biogenesis
BenefitsADHD/Focus, Antioxidation, Bipolar, Cancer Prevention, Depression, General Health, Higher Cognition, Illness Prevention, Longevity, Memory
Stacks-well-withSertraline, serotonergic antidepressants (WITH CAUTION)

Tropisetron

BasenameTropisetron
Typeα7 nAChR agonist
Targetsα7 nAChR, 5-HT3 receptor, SIRT1
PathwaysAcetylcholine, cAMP, serotonin
ProcessesLong Term Potentiation, neurogenesis
Brain-regionsprefrontal cortex, hippocampus
Stacks-well-withNicotine (enhances and prolongs effects)

Usmarapride

BasenameUsmarapride
Type5-HT4 partial agonist
Targets5-HT4 receptor
PathwayscAMP, BDNF, serotonin
ProcessesLong Term Potentiation, neurogenesis
Brain-regionshippocampus
Stacks-well-withACD-856, Tropisetron

Semax

BasenameSemax
Typenootropic peptide
TargetsTrkB
PathwaysBDNF, dopamine, serotonin, norepinephrine
Processesneurogenesis
BenefitsADHD/Focus, Anxiety, Wakefulness

BPAP

BasenameBPAP
Typecatecholamine activity enhancer
Pathwaysdopamine, norepinephrine
BenefitsADHD/Focus, Depression, Longevity, Motivation

ABT-089

BasenameABT-089
Typeα4β2 nAChR partial agonist
Targetsα4β2 nicotinic receptor
PathwaysAcetylcholine
Processesattentional filtering, working memory
Brain-regionsprefrontal cortex, thalamus
BenefitsAttention, Working memory, Cognitive filtering
Stacks-well-withTropisetron

Agmatine

BasenameAgmatine
TypeNMDA antagonist
TargetsNMDA receptor, imidazoline receptor
Pathwaysnitric oxide, polyamine pathway
BenefitsAntioxidation, Anxiety, Bipolar, Cancer Prevention, Depression, Drug Cravings, General Health, Nutritional Supplementation, Sleep

BPN14770

BasenameBPN14770
TypePDE4D inhibitor
TargetsPDE4D
PathwayscAMP, PKA, CREB, BDNF
ProcessesLong Term Potentiation, synaptic consolidation
Brain-regionshippocampus, prefrontal cortex
BenefitsMemory consolidation, LTP, Neuroplasticity
Stacks-well-withACD-856

Fasoracetam

BasenameFasoracetam
TypemGluR2/3 agonist / GABA-B upregulator
TargetsmGluR2, mGluR3, GABA-B receptor
PathwaysGlutamate, GABA
Processesreceptor resensitization, E/I balance
Brain-regionsprefrontal cortex, hippocampus
BenefitsReceptor resensitization, E/I balance restoration, Anxiolytic
Stacks-well-withTUDCA, AF710B

KW-6356

BasenameKW-6356
TypeA2A adenosine receptor antagonist
TargetsA2A adenosine receptor, D2 receptor
Pathwaysdopamine, adenosine, cAMP
Processesdopaminergic signaling
Brain-regionsstriatum, basal ganglia
BenefitsMotivation, Drive, Goal-directed behavior
Stacks-well-withBromantane

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